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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3455 |
Merestinib
LY2801653 |
Discoidin Domain Receptor (DDR); FLT; c-Met/HGFR; ROS; ROS Kinase | Angiogenesis; Immunology/Inflammation; Tyrosine Kinase/Adaptors |
Merestinib (LY2801653) 是一种有效的口服生物可利用的具有抗肿瘤活性的c-Met 抑制剂。 | |||
T4349 |
Sitravatinib
MG516,MGCD516 |
Discoidin Domain Receptor (DDR); VEGFR; FLT; Trk receptor; TAM Receptor; c-Kit; Ephrin Receptor | Angiogenesis; Tyrosine Kinase/Adaptors |
Sitravatinib (MGCD516) 是一种有口服活性的受体酪氨酸激酶抑制剂。它单独使用即具有有效的抗肿瘤功效,且通过促进抗肿瘤免疫微环境增强了 PD-1 阻断的活性。 | |||
T9659 |
LCB 03-0110
3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol |
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
LCB 03-0110 (3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol) 是一种盘状结构域受体家族酪氨酸激酶的强效抑制剂,可强烈抑制多种酪氨酸激酶,包括 c-Src 家族、脾酪氨酸激酶、布鲁顿酪氨酸激酶和血管内皮生长因子受体 2,它们对免疫很重要细胞信号传导和炎症反应。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01289 |
DDR1 Protein, Human, Recombinant (His)
RTK6,DDR,TRKE,PTK3,NTRK4,NEP,PTK3A,MCK10,EDDR1,HGK2,CD167,CA... |
Human | HEK293 Cells |
DDR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is A0A024RCQ1. | |||
TMPY-03642 |
DDR2 Protein, Rhesus, Recombinant (hFc)
discoidin domain receptor tyrosine |
Rhesus | HEK293 Cells |
DDR2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 7.0 kDa and the accession number is XP_001118219.1. | |||
TMPY-03166 |
DDR2 Protein, Rat, Recombinant (His)
discoidin domain receptor tyrosine |
Rat | HEK293 Cells |
DDR2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.9 kDa and the accession number is B1WC09. | |||
TMPY-03098 |
DDR2 Protein, Rat, Recombinant (hFc)
discoidin domain receptor tyrosine |
Rat | HEK293 Cells |
DDR2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.5 kDa and the accession number is B1WC09. | |||
TMPY-03593 |
DDR2 Protein, Rhesus, Recombinant (His)
discoidin domain receptor tyrosine |
Rhesus | HEK293 Cells |
DDR2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.1 kDa and the accession number is XP_001118219.1. | |||
TMPY-03541 |
DDR1 Protein, Rat, Recombinant (hFc)
Drd1,Cak,discoidin domain receptor tyr... |
Rat | HEK293 Cells |
DDR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.9 kDa and the accession number is Q6MG19. | |||
TMPY-03313 |
DDR1 Protein, Rat, Recombinant (His)
discoidin domain receptor tyrosine |
Rat | HEK293 Cells |
DDR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is Q6MG19. | |||
TMPY-01728 |
DDR2 Protein, Mouse, Recombinant (His)
AW495251,discoidin domain receptor tyr... |
Mouse | HEK293 Cells |
DDR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.88 kDa and the accession number is Q62371. | |||
TMPY-02506 |
DDR1 Protein, Mouse, Recombinant (hFc)
AI323681,CD167a,Nep,Cak,PTK3A,6030432F18,discoidin ... |
Mouse | HEK293 Cells |
DDR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71 kDa and the accession number is Q03146-1. | |||
TMPY-04442 |
DDR1 Protein, Mouse, Recombinant (His & GST)
6030432F18,Nep,Cak,AI323681,CD167a,discoidin domain... |
Mouse | Baculovirus Insect Cells |
DDR1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.8kDa and the accession number is Q03146-2. | |||
TMPY-02310 |
DDR1 Protein, Mouse, Recombinant (His)
CD167a,discoidin domain receptor tyros... |
Mouse | HEK293 Cells |
DDR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa and the accession number is Q03146-1. | |||
TMPY-03625 |
DDR2 Protein, Human, Recombinant (His)
MIG20a,CD167,discoidin domain receptor |
Human | HEK293 Cells |
DDR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.1 kDa and the accession number is Q16832. | |||
TMPY-04361 |
DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)
discoidin domain receptor tyrosine |
Human | Baculovirus Insect Cells |
DDR2 Protein, Human, Recombinant (aa 422-855, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 77.1 kDa and the accession number is Q16832. | |||
TMPY-00773 |
DDR2 Protein, Human, Recombinant (hFc)
MIG20a,TYRO10,CD167,NTRKR3,discoidin domain rec... |
Human | HEK293 Cells |
DDR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.4 kDa and the accession number is Q16832. | |||
TMPH-01297 |
DDR1 Protein, Human, Recombinant (aa 21-417, His)
EDDR1,MCK-10,Epithelial discoidin domain-containing... |
Human | HEK293 Cells |
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell... | |||
TMPY-04382 |
DDR1 Protein, Human, Recombinant (aa 444-913, His & GST)
discoidin domain receptor tyrosine |
Human | Baculovirus Insect Cells |
DDR1 Protein, Human, Recombinant (aa 444-913, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80 kDa and the accession number is Q08345-1. |